The lifetime diagnosis of lymphoid infiltration of the lungs is extremely difficult. An objective criterion for the diagnosis of lymphoid infiltration of the lungs and pleura, as well as other organs, is morphological examination. However, a lively histological examination of light biopsies is difficult because of the invasiveness of all types of biopsies.

He identified the signs that are most common in CLL patients, which may indicate the development of a specific lymphoid lesion of the lungs and pleura with an accuracy of 94%. I) Statistically significant signs – 1) B-symptoms (a symptom complex indicating the activity of the tumor process, the degree of tumor intoxication) (p = 0.0002), 2) the presence of enlarged bifurcation lymph nodes during computed tomography (p = 0.003), 3) hemoglobin is below 100g / l (p = 0.01), 4) an increase in intrathoracic lymph nodes during X-ray (p = 0.03). II) Statistically insignificant signs – 1) complaints of patients for the presence of difficulty breathing (p = 0.09), 2) enlarged lymph nodes during radiography (p = 0.14), 3) general somatic status of EKOG WHO 2-4 (p = 0.21).

An informative method for diagnosing leukemia of the lung is X-ray examination.
However, many authors note that radiological and clinical differential diagnosis of inflammatory processes in the lungs and leukemic infiltration is extremely difficult, since specific and nonspecific changes are often combined. The peculiarity of leukemic infiltrates is poor clinical symptoms, its progression against the background of antibacterial therapy, more often bilateral lung injury. In contrast, pneumonia reveals small and large-focal darkening, often one-sided; antibacterial drugs have a certain effect.